As new drug development for HIV (AIDS) continues, a drug called Maraviroc has been shown to reverse memory loss in mice.
The HIV virus, known as AIDS, has been posing a great threat to humanity for years. While research on the subject continues, some surprising events may occur in this process. In this week’s issue of the journal Nature, a surprising detail about a drug called Maraviroc emerged.
It was noticed that the drug Maraviroc , which was tested on mice, solved a different problem than its purpose. It has been proven that the drug, which provides a significant restoration of memory, has an effect on humans as well.
Maraviroc appears to restore memory loss
First tested in mice, the drug was found to play an important role in improving memory ability. However, it was stated that the same situation had an effect on humans as well. Just like in mice, the drug has been proven to have an effect on the human brain in a number of nervous system-related problems.
Making a statement on the subject, the head of neurology at the University of California, Dr. S. Thomas Carmichael , on medicine; “It may have an effect in Alzheimer’s disease, stroke, Parkinson’s, and also spinal cord injuries,” he said.
Experts define associative memory, the linking of memories that occur at the same time . This decreases with advancing age and can be almost completely impaired in people with Alzheimer’s disease.
Alcino Silva, who played an important role in the development of the drug called Maraviroc, emphasized that problems with attachment memory can occur in people who do not have difficulty forming new memories. Silva then carried out several tests by taking a molecule called CRR5 into the laboratory to clarify the situation.
So what is the CCR5 molecule?
For those who don’t know, CCR5 is an important part of the immune system . Found in the human body, CCR5 is tasked with helping the brain separate recent memories from old ones. Because without this separation, it would not even be possible to remember a moment we lived a short time ago.
One wondered why the CCR5 molecule causes associated memory problems in humans and mice as they age. Fortunately, Silva found the reason for this as a result of his tests. Silva, who tested the first tests in mice with the CCR5-disabled form, concluded that in these mice, memories were linked one week apart. But in typical mice, memories proved to be linked only a few hours apart. As a result, Silva stated that the drug restores the memory connection and has an important share in memories. Maraviroc, which is promising for many diseases, according to experts; It can be used in diseases such as stroke, Alzheimer’s and Parkinson’s.